Failure of Thromboprophylaxis in Pregnancy Caused by Dual Deficiencies of Protein S and Protein C

ABSTRACT

Protein S and protein C deficiencies are commonly identified biochemical abnormalities associated with a hypercoagulable state; they result in an increased incidence of venous thromboembolism. We report the case of a pregnant woman with dual deficiencies of protein S and protein C, who encountered a venous thromboembolism 7 days postpartum despite of the use of danaparoid.

KEYWORDS

Pregnancy - thrombosis - protein C - protein S - thromboprophylaxis

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